Individualized therapeutic approaches for relapsed and refractory pediatric ependymomas: a single institution experience
We demonstrated the feasibility and good safety profile. Promising was the effect of immunotherapy on ZFTA-positive ependymomas. However, further research is required to establish the most effective approach for achieving sustained remission in these patients.
Authors
- Marta Ježová (ORCID: https://orcid.org/0000-0001-5611-331X)
- Zdeněk Pavelka
- Jakub Neradil (ORCID: https://orcid.org/0000-0001-6781-7099)
- Pavel Tinka
- Hana Pálová (ORCID: https://orcid.org/0000-0001-8803-9433)
- Klára Vejmělková
- Petra Pokorná (ORCID: https://orcid.org/0000-0003-1037-878X)
- Ondřej Slabý (ORCID: https://orcid.org/0000-0002-8450-0584)
- Jaroslav Štěrba (ORCID: https://orcid.org/0000-0002-8482-8352)
- Michal Kýr (ORCID: https://orcid.org/0000-0001-6623-8386)
Institutions
- Central European Institute of Technology (CZ)
- Masaryk University (CZ)
- University Hospital Brno (CZ)
- International Clinical Research Center, St. Anne's University Hospital Brno (CZ)
- Central European Institute of Technology (AT)
- St. Anne's University Hospital Brno (CZ)
Publication Details
- Journal
- Journal of Neuro-Oncology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1007/s11060-025-05004-1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministerstvo Školství, Mládeže a Tělovýchovy
- Ministerstvo Zdravotnictví Ceské Republiky
- Central European Institute of Technology
- Masarykova Univerzita