Central and peripheral adiposity and premenopausal breast cancer risk: a pooled analysis of 440,179 women
Our analyses did not support an association between central adiposity and overall premenopausal breast cancer risk after adjustment for BMI. However, our findings suggest associations might differ by breast cancer hormone receptor and intrinsic subtypes.
Authors
- Minouk J. Schoemaker (ORCID: https://orcid.org/0000-0001-8403-2234)
- A. Heather Eliassen (ORCID: https://orcid.org/0000-0002-3961-6609)
- Laura Baglietto (ORCID: https://orcid.org/0000-0002-8193-7529)
- Graham G. Giles (ORCID: https://orcid.org/0000-0003-4946-9099)
- Jessica Clague DeHart (ORCID: https://orcid.org/0000-0002-2298-3146)
- Michael E. Jones (ORCID: https://orcid.org/0000-0001-7479-3451)
- Hans‐Olov Adami (ORCID: https://orcid.org/0000-0001-9592-5791)
- Victoria A. Kirsh (ORCID: https://orcid.org/0000-0003-2422-2225)
- Roger Laughlin Milne (ORCID: https://orcid.org/0000-0001-5764-7268)
- LARS JOHAN VATTEN (ORCID: https://orcid.org/0000-0003-2333-5252)
- Rulla M. Tamimi (ORCID: https://orcid.org/0000-0003-2306-8668)
- Taylor D. Ellington (ORCID: https://orcid.org/0000-0002-5938-7719)
- Hazel B. Nichols (ORCID: https://orcid.org/0000-0003-0972-1560)
- Katie M. O’Brien (ORCID: https://orcid.org/0000-0002-1931-1349)
- Dale P. Sandler (ORCID: https://orcid.org/0000-0002-6776-0018)
- Thomas E. Rohan (ORCID: https://orcid.org/0000-0001-6897-4045)
- Anne Zeleniuch‐Jacquotte (ORCID: https://orcid.org/0000-0001-9350-1303)
- Lauren B. Wright (ORCID: https://orcid.org/0000-0002-4119-0037)
- Kimberly A. Bertrand (ORCID: https://orcid.org/0000-0002-4565-7618)
- Serena C. Houghton (ORCID: https://orcid.org/0000-0001-8833-9065)
- Hannah Lui Park (ORCID: https://orcid.org/0000-0001-9973-1396)
- Elisabete Weiderpass (ORCID: https://orcid.org/0000-0003-2237-0128)
- Walter Churchill Willett (ORCID: https://orcid.org/0000-0003-1458-7597)
- Gianluca Severi (ORCID: https://orcid.org/0000-0001-7157-419X)
- Julie R. Palmer (ORCID: https://orcid.org/0000-0002-6534-335X)
- Yu Chen (ORCID: https://orcid.org/0000-0002-1519-4894)
- Anthony J Swerdlow
- Wei Zheng (ORCID: https://orcid.org/0009-0008-7731-248X)
- Xiao-Ou Shu
- Clarice Ring Weinberg (ORCID: https://orcid.org/0000-0002-7713-8556)
Institutions
- University of Pisa (IT)
- Boston University (US)
- Ontario Institute for Cancer Research (CA)
- University of North Carolina at Chapel Hill (US)
- Brigham and Women's Hospital (US)
- National Institutes of Health (US)
- Albert Einstein College of Medicine (US)
- Harvard University (US)
- Claremont Graduate University (US)
- Institute of Cancer Research (GB)
- The University of Melbourne (AU)
- University of Oslo (NO)
- University of Toronto (CA)
- Cancer Council Victoria (AU)
- Vanderbilt University (US)
- University of California, Irvine (US)
- Norwegian University of Science and Technology (NO)
- Cornell University (US)
- University of Massachusetts Amherst (US)
- Karolinska Institutet (SE)
- National Institute of Environmental Health Sciences (US)
- Monash Health (AU)
- Public Health Ontario (CA)
- Centre international de recherche sur le cancer (FR)
- University of Florence (IT)
- University of York (GB)
- Monash University (AU)
- New York University (US)
Publication Details
- Journal
- Breast Cancer Research
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1186/s13058-025-01995-x
- Citations
- 3
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 3.14
Funders
- Breast Cancer Research Foundation
- Susan G. Komen
- Centers for Disease Control and Prevention
- National Cancer Institute