Redefining the high variable genes by optimized LOESS regression with positive ratio
By preserving key biological information through feature selection, GLP provides informative features to enhance the accuracy and effectiveness of downstream analyses.
Authors
- Zehua Jing (ORCID: https://orcid.org/0000-0002-7275-0869)
- Xun William Xu (ORCID: https://orcid.org/0000-0001-6294-8153)
- Yue Xie
- Fang Qi (ORCID: https://orcid.org/0009-0004-9006-3554)
- Haiqiao Pan
Institutions
- BGI Group (China) (CN)
- University of Chinese Academy of Sciences (CN)
- BGI Research (CN)
Publication Details
- Journal
- BMC Bioinformatics
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1186/s12859-025-06112-5
- Citations
- 25
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 20.15
Funders
- National Key Research and Development Program of China