Uveitis in child treated for acute myeloblastic leukemia: Do not overlook poststreptococcal inflammation

IntroductionPoststreptococcal uveitis is among the immune complications following strep infections.Case descriptionA patient treated for acute myeloblastic leukemia presented with febrile neutropenia 22 days after consolidation chemotherapy including cytarabine. Diagnosed with <i>Streptococcus mitis</i> bacteremia, she subsequently presented with uveitis in her right eye, linked to the previous infection through positive anti-streptolysin O and negative microbiological test results. Topical treatment resulted in complete recovery.ConclusionThis unprecedented presentation of post-<i>S. mitis</i> uveitis reveals the potential for misdiagnosis of ocular manifestations after cytarabine treatment. Furthermore, neutropenia and profound lymphopenia should not prevent both the ophthalmologist and the hematologist from considering poststreptococcal immune complications.

Authors

Institutions

Publication Details

Journal
European Journal of Ophthalmology
Published
2025-04-15
DOI
https://doi.org/10.1177/11206721251334164
Citations
1
Primary Topic
Streptococcal Infections and Treatments
Type
article
Field-Weighted Citation Impact
1.88
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Uveitis in child treated for acute myeloblastic leukemia: Do not overlook poststreptococcal inflammation

Audrey Grain, Baptiste Le Calvez, C. Couret, Margaux Camuset et al.
1 citations
European Journal of Ophthalmology
Streptococcal Infections and Treatments
1.88
article

Uveitis in child treated for acute myeloblastic leukemia: Do not overlook poststreptococcal inflammation

Audrey Grain, Baptiste Le Calvez, C. Couret, Margaux Camuset, Philippe Gardeton, Inés Chabbi
article en
1 citations

Abstract

IntroductionPoststreptococcal uveitis is among the immune complications following strep infections.Case descriptionA patient treated for acute myeloblastic leukemia presented with febrile neutropenia 22 days after consolidation chemotherapy including cytarabine. Diagnosed with <i>Streptococcus mitis</i> bacteremia, she subsequently presented with uveitis in her right eye, linked to the previous infection through positive anti-streptolysin O and negative microbiological test results. Topical treatment resulted in complete recovery.ConclusionThis unprecedented presentation of post-<i>S. mitis</i> uveitis reveals the potential for misdiagnosis of ocular manifestations after cytarabine treatment. Furthermore, neutropenia and profound lymphopenia should not prevent both the ophthalmologist and the hematologist from considering poststreptococcal immune complications.

European Journal of OphthalmologyVol. 35(4)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers (FR), Nantes Université (FR)
Good health and well-being
Openalex Percentile: Top 17%
Streptococcal Infections and Treatments
1.88
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.