Plasma proteomic biomarkers of physical frailty in heart failure: a propensity score matched discovery-based pilot study
Proteomic biomarkers related to the immune system, stress response, and detoxification were differentially expressed between physically frail and non-physically frail adults with HF.
Authors
- Samantha Powell (ORCID: https://orcid.org/0000-0003-2670-0024)
- Beth A. Habecker (ORCID: https://orcid.org/0000-0002-4658-8730)
- Susan Joseph (ORCID: https://orcid.org/0000-0002-0297-5405)
- Jon Jacobs (ORCID: https://orcid.org/0000-0003-0557-7338)
- Noelle Pavlovic (ORCID: https://orcid.org/0000-0002-1607-6849)
- Mary C. Davis (ORCID: https://orcid.org/0000-0002-3226-4516)
- Marina Gritsenko (ORCID: https://orcid.org/0000-0001-9992-9829)
- Quin E. Denfeld (ORCID: https://orcid.org/0000-0001-7568-9568)
- Christopher Seungkyu Lee (ORCID: https://orcid.org/0000-0002-2510-4071)
Institutions
- Boston College (US)
- Pacific Northwest National Laboratory (US)
- Johns Hopkins University (US)
- Thomas Jefferson University (US)
- Oregon Health & Science University (US)
- Oregon Health and Science University Hospital (US)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1186/s12872-025-04725-5
- Citations
- 1
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 1.22
Funders
- National Institutes of Health