Hyperactive Catatonia in an Adolescent With Prader-Willi Syndrome

Catatonia, a neuropsychiatric syndrome, has been increasingly recognized as a possible complication of Prader-Willi syndrome (PWS). There is limited research surrounding catatonia and its sequelae in PWS. Given the scarcity and severity of catatonia in pediatric age, there is a need to expand on the available literature. We present a case of hyperactive catatonia in an adolescent with PWS. After obtaining a thorough history, we followed her progression from motor symptoms to developing psychotic features. Although her presentation required multiple doses of lorazepam, it was shown to be consistently effective in treating her catatonia during her hospital stay.