Long‐Term Outcomes of Belatacept Versus Tacrolimus Following T‐Cell Depleting Induction in Adult Kidney Transplantation
This is the largest longitudinal study to compare outcomes of belatacept versus tacrolimus-based therapy following T-cell depleting induction. Belatacept was associated with improved graft function despite an increased acute rejection rate. There was no difference in overall graft or patient survival compared to tacrolimus. This study suggests that belatacept-based therapy is not inferior to tacrolimus-based therapy following T-cell depletion.
Authors
- Laura Newton (ORCID: https://orcid.org/0000-0002-3625-1392)
- M. G. Daly (ORCID: https://orcid.org/0000-0002-3733-2530)
- Michael Chobanian
- Asha Zimmerman (ORCID: https://orcid.org/0000-0001-8135-8458)
- Thomas W. D'Angelo (ORCID: https://orcid.org/0009-0004-8330-4436)
Institutions
- Dartmouth College (US)
- White River Junction VA Medical Center (US)
- Dartmouth Psychiatric Research Center (US)
- Dartmouth Health (US)
Publication Details
- Journal
- Clinical Transplantation
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1111/ctr.70154
- Citations
- 1
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.99
Funders
- U.S. Department of Veterans Affairs