Toxic metals and metalloids in collagen supplements of fish and jellyfish origin: Risk assessment for daily intake
Arsenic was the most abundant element detected, with mean values of 0.59 ± 0.28 mg/kg, followed by Pb (0.13 ± 0.02 mg/kg). Significant variability was observed between brands. Hg was detectable in only 12% of the samples. Marine collagen samples derived from jellyfish and <i>Scomber scombrus</i> skin extract showed no detectable toxic metals or metalloids. None of the samples exceeded EU regulatory limits, and ADDs were consistently below TDIs, indicating safety for consumption at recommended doses. However, it is recommended that food safety regulations be updated to account for potential cumulative risks from simultaneous intake of contaminated supplements.
Authors
- Vincenzo Ferrantelli (ORCID: https://orcid.org/0000-0002-4911-5074)
- Licia Pantano (ORCID: https://orcid.org/0000-0002-4044-9449)
- Maria Drussilla Buscemi (ORCID: https://orcid.org/0000-0002-8452-0278)
- Gaetano Cammilleri (ORCID: https://orcid.org/0000-0001-6300-6571)
- Gianluigi Maria Lo Dico (ORCID: https://orcid.org/0000-0001-8537-0016)
- Vittorio Calabrese (ORCID: https://orcid.org/0000-0002-0478-985X)
- Marina Tortorici
- Andrea Macaluso (ORCID: https://orcid.org/0000-0003-3105-2383)
- Francesco Giuseppe Galluzzo (ORCID: https://orcid.org/0000-0001-9262-116X)
- Andrea Pulvirenti (ORCID: https://orcid.org/0000-0002-8479-8878)
- Ursula M. Jacob
Institutions
- University of Modena and Reggio Emilia (IT)
- University of Catania (IT)
- Istituto Zooprofilattico Sperimentale Della Sicilia (IT)
Publication Details
- Journal
- Open Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1515/med-2025-1141
- Citations
- 4
- Primary Topic
- Heavy metals in environment
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Ministero della Salute