Macrophage requirements for abatacept response in rheumatoid arthritis

ABA response in RA patients is associated with a particular pro-inflammatory macrophage phenotype pre-treatment and IDO is required for ABA effect. These findings reveal predictive markers of ABA response and the involvement of the IDO pathway.

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Publication Details

Journal
Clinical and Experimental Rheumatology
Published
2024-09-30
DOI
https://doi.org/10.55563/clinexprheumatol/s42d3g
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Macrophage requirements for abatacept response in rheumatoid arthritis

Manuel Fréret, Gaëtan Riou, Olivier Boyer, Pauline Brevet et al.
Clinical and Experimental Rheumatology
Systemic Lupus Erythematosus Research
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Macrophage requirements for abatacept response in rheumatoid arthritis

Manuel Fréret, Gaëtan Riou, Olivier Boyer, Pauline Brevet, Sophie Candon, Olivier Vittecoq, Thierry Lequerré, B. De Maleprade, Baptiste Gérard
article en

Abstract

ABA response in RA patients is associated with a particular pro-inflammatory macrophage phenotype pre-treatment and IDO is required for ABA effect. These findings reveal predictive markers of ABA response and the involvement of the IDO pathway.

Clinical and Experimental RheumatologyVol. 43(5)
Inserm (FR), Normandie Université (FR), Université de Rouen Normandie (FR)
Zero hunger
Openalex Percentile: Top 56%
Systemic Lupus Erythematosus Research
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