The Relationship Between Alkaline Phosphatase and Periodontitis: The Mediating Role of Cranial Bone Mineral Density
Elevated serum ALP levels were positively associated with an increased risk of periodontitis, and cranial BMD partially mediated this association. Monitoring ALP levels may contribute to the early diagnosis and intervention of periodontitis, while targeting bone metabolism regulation could offer a novel direction for the treatment of periodontitis.
Authors
- Yang Miao (ORCID: https://orcid.org/0000-0002-0454-8677)
- Ching‐Lan Cheng (ORCID: https://orcid.org/0000-0002-7201-8491)
- Qiuling Tang (ORCID: https://orcid.org/0000-0002-0443-9761)
- Qingfeng Xiao
Institutions
- Hubei University of Arts and Science (CN)
- Xiangyang Central Hospital (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1016/j.identj.2025.03.016
- Citations
- 2
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 2.93