Correlation between Olink and SomaScan proteomics platforms in adults with a Fontan circulation
In adults with a Fontan circulation, correlations between plasma proteins measured by Olink and SomaScan varied widely, approximately in line with prior reports in other populations. While these tools may be uniquely useful to generate hypotheses, specifically regarding potential molecular mechanisms, more definitive inference requires independent validation.
Authors
- Miriam Michel (ORCID: https://orcid.org/0000-0002-3626-3270)
- Michael J. Landzberg
- Kristian C. Becker (ORCID: https://orcid.org/0000-0001-9550-9560)
- Robert E. Gerszten (ORCID: https://orcid.org/0000-0002-6767-7687)
- Fernando Baraona Reyes
- David M. Leone (ORCID: https://orcid.org/0000-0002-4296-4081)
- Renaud David (ORCID: https://orcid.org/0009-0003-8746-5758)
- Mark Benson
- Alexander R. Opotowsky (ORCID: https://orcid.org/0000-0002-6107-2281)
- Ismael Assi (ORCID: https://orcid.org/0000-0003-4310-7396)
Institutions
- Brigham and Women's Hospital (US)
- Cincinnati Children's Hospital Medical Center (US)
- Boston Children's Hospital (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Innsbruck Medical University (AT)
- Université Paris Cité (FR)
- Universidad Europea Miguel de Cervantes (ES)
- Sorbonne Paris Cité (FR)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- International Journal of Cardiology Congenital Heart Disease
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1016/j.ijcchd.2025.100584
- Citations
- 1
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.35