Quantifying the effect of IMPEDE-FX packing rate and volume on pressure-normalized principal wall strain in an idealized 3D-printed aneurysm model

The present findings suggest that rapid, high-volume filling of IMPEDE-FX embolization plugs results in a reduction in wall <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mover><mml:msub><mml:mi>ε</mml:mi> <mml:mrow><mml:mi>ρ</mml:mi> <mml:mo>+</mml:mo></mml:mrow> </mml:msub> <mml:mo>¯</mml:mo></mml:mover> </mml:mrow> </mml:math> /PP, independent of thrombus formation. Fully expanded embolization plugs in aggregate limit pulsatile aortic sac displacement likely contribute to a greater reduction in overall wall strain compared with low packing volumes. These findings may inform clinical application for this device, supporting a rapid and high-volume deployment strategy for greater reduction in <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mover><mml:msub><mml:mi>ε</mml:mi> <mml:mrow><mml:mi>ρ</mml:mi> <mml:mo>+</mml:mo></mml:mrow> </mml:msub> <mml:mo>¯</mml:mo></mml:mover> </mml:mrow> </mml:math> /PP status post endovascular aneurysm repair.