Ruptured uterine pyomyoma with multiorgan dysfunction syndrome

A woman with a history of chronic hypertension, no previous pregnancies and a recent myomectomy presented to the emergency department with fever, vomiting, diarrhoea and abdominal pain. She showed signs of septic shock, acute kidney injury and respiratory failure. Imaging revealed a large necrotic fibroid, hydrosalpinx, ascites and pleural effusion. Blood cultures showed <i>Escherichia coli</i> growth. She underwent emergency surgery for total abdominal hysterectomy, bilateral salpingoophorectomy and hysteroscopy. Intraoperatively, purulent discharge was found, and cultures confirmed <i>E. coli</i> infection. Pathology revealed leiomyomata with degenerative changes, benign endometrial polyps and endometriosis. Postoperatively, she received intensive care and showed gradual improvement, eventually being discharged in a stable condition. Follow-up appointments showed resolution of symptoms, wound healing and no infection recurrence. Antibiotics were discontinued, and the pleural drain was removed. Overall, the patient had a successful recovery with no complications noted during follow-up.

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Publication Details

Journal
BMJ Case Reports
Published
2025-04-01
DOI
https://doi.org/10.1136/bcr-2024-261454
Primary Topic
Uterine Myomas and Treatments
Type
article
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article

Ruptured uterine pyomyoma with multiorgan dysfunction syndrome

Rozilla Sadia Khan, Faryal Anees, Dur-E-Shahwar, Tehreem Khalid
BMJ Case Reports
Uterine Myomas and Treatments
article

Ruptured uterine pyomyoma with multiorgan dysfunction syndrome

Rozilla Sadia Khan, Faryal Anees, Dur-E-Shahwar, Tehreem Khalid
article en

Abstract

A woman with a history of chronic hypertension, no previous pregnancies and a recent myomectomy presented to the emergency department with fever, vomiting, diarrhoea and abdominal pain. She showed signs of septic shock, acute kidney injury and respiratory failure. Imaging revealed a large necrotic fibroid, hydrosalpinx, ascites and pleural effusion. Blood cultures showed <i>Escherichia coli</i> growth. She underwent emergency surgery for total abdominal hysterectomy, bilateral salpingoophorectomy and hysteroscopy. Intraoperatively, purulent discharge was found, and cultures confirmed <i>E. coli</i> infection. Pathology revealed leiomyomata with degenerative changes, benign endometrial polyps and endometriosis. Postoperatively, she received intensive care and showed gradual improvement, eventually being discharged in a stable condition. Follow-up appointments showed resolution of symptoms, wound healing and no infection recurrence. Antibiotics were discontinued, and the pleural drain was removed. Overall, the patient had a successful recovery with no complications noted during follow-up.

BMJ Case ReportsVol. 18(4)
Aga Khan University Hospital (PK)
Good health and well-being
Openalex Percentile: Top 90%
Uterine Myomas and Treatments
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Ruptured uterine pyomyoma with multiorgan dysfunction syndrome — Rozilla Sadia Khan, Faryal Anees, et al. · BMJ Case Reports (2025) | TGRS Research Map | TGRS