Asymptomatic Ileal Intussusception: A Rare Twist in a Marginal B-cell Lymphoma

A 75-year-old male patient with a history of type 2 diabetes, hypertension, interstitial pneumonitis, and gastroesophageal reflux disease underwent a screening colonoscopy that revealed a 3-4 cm ulcerated ileal tumor. Subsequent diagnostic evaluations, including endoscopy and contrast-enhanced CT, identified additional findings of chronic atrophic gastritis with <i>Helicobacter pylori</i> and ileocecal intussusception. Histopathological analysis confirmed a marginal zone B-cell lymphoma with CD20+ expression and negative surgical margins following a right hemicolectomy. <i>H. pylori</i> eradication was successful, and the patient remains asymptomatic with no evidence of recurrence. It can present atypically, including intussusception. Early detection and appropriate management are crucial for achieving favorable outcomes.