Bispecific Bridge Helps NK Cells Target Lymphoma

A CD30×CD16A bispecific antibody is helping off-the-shelf natural killer cells home in on cancer targets, showing strong responses in patients with relapsed or refractory lymphoma. Early clinical success has prompted further testing, though changes in the treatment protocol could complicate efforts to replicate the results.

Publication Details

Journal
Cancer Discovery
Published
2025-01-01
DOI
https://doi.org/10.1158/2159-8290.cd-nw2025-0029
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
0.00
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article

Bispecific Bridge Helps NK Cells Target Lymphoma

Cancer Discovery
Immune Cell Function and Interaction
article

Bispecific Bridge Helps NK Cells Target Lymphoma

article en

Abstract

A CD30×CD16A bispecific antibody is helping off-the-shelf natural killer cells home in on cancer targets, showing strong responses in patients with relapsed or refractory lymphoma. Early clinical success has prompted further testing, though changes in the treatment protocol could complicate efforts to replicate the results.

Cancer Discovery
Zero hunger
Openalex Percentile: Top 92%
Immune Cell Function and Interaction
DOISourceOpenAlex
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Bispecific Bridge Helps NK Cells Target Lymphoma · Cancer Discovery (2025) | TGRS Research Map | TGRS