Comparative study on the sensitivity of lumbar puncture and external ventricular drainage cerebrospinal fluid in the diagnosis of central nervous system infections after craniotomy
LP CSF demonstrates higher sensitivity than EVD CSF for early diagnosis of CNSIs in post-craniotomy patients with indwelling EVDs. In clinical practice, when EVD results are negative but there is high clinical suspicion of CNSIs, concurrent LP should be performed for further confirmation.
Authors
- Hongmiao Xu
- Zhen-Nan Ye (ORCID: https://orcid.org/0000-0002-1237-1971)
- Jincan Zhang (ORCID: https://orcid.org/0000-0002-7131-4491)
- Fang Zuo
- Daniel Wen (ORCID: https://orcid.org/0000-0002-2724-5310)
- Peng Liu (ORCID: https://orcid.org/0000-0003-3453-2278)
- Dong Liu (ORCID: https://orcid.org/0000-0001-7603-8927)
- Tingting Lin (ORCID: https://orcid.org/0000-0002-6061-2311)
- Yongzhong Liao
- Yue Tang
Institutions
- Peking University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Fourth Hospital of Changsha (CN)
- Peking University Third Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-04-15
- DOI
- https://doi.org/10.3389/fneur.2025.1586394
- Citations
- 1
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province