Spatial Transcriptomic Landscape of Brain Metastases from Triple-Negative Breast Cancer: Comparison of Primary Tumor and Brain Metastases Using Spatial Analysis
This study provides novel insights into the transcriptional landscapes in TNBC BM using spRNA-seq, emphasizing the role of neuron-tumor interactions and immune dynamics. These findings suggest new therapeutic strategies and underscore the importance of further research.
Authors
- Hun Ho Park (ORCID: https://orcid.org/0000-0002-2526-9693)
- Jihwan Yoo (ORCID: https://orcid.org/0000-0001-8746-1245)
- Yoon Jin (ORCID: https://orcid.org/0000-0002-5967-4064)
- In Ho Park (ORCID: https://orcid.org/0000-0003-2190-5469)
- Jee Hung Kim (ORCID: https://orcid.org/0000-0002-9044-8540)
- Hyun Jung Kim (ORCID: https://orcid.org/0000-0002-6617-4578)
- Sora Lee (ORCID: https://orcid.org/0000-0002-0075-7324)
Institutions
- Yonsei University (KR)
- Korea University (KR)
- Gangnam Severance Hospital (KR)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2025-04-15
- DOI
- https://doi.org/10.4143/crt.2025.033
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00