Investigating the renoprotective effects of Polygonatum sibiricum polysaccharides (PSP) on D-galactose-induced aging mice: insights from gut microbiota and metabolomics analyses
PSP protects against age-related kidney damage by modulating gut microbiota and metabolic pathways, highlighting its therapeutic potential for kidney aging through the gut-kidney axis.
Authors
- Shuihan Zhang (ORCID: https://orcid.org/0000-0003-0169-2267)
- Rui Huang (ORCID: https://orcid.org/0000-0002-5680-736X)
- Wen Li Xie (ORCID: https://orcid.org/0000-0003-3967-155X)
- Taoli Sun (ORCID: https://orcid.org/0000-0003-0598-9228)
- R. Che
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- The First People's Hospital of Changde (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-04-15
- DOI
- https://doi.org/10.3389/fmicb.2025.1550971
- Citations
- 1
- Primary Topic
- Antioxidants, Aging, Portulaca oleracea
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province