Low-frequency rTMS modulates small-world network properties in an AVH-related brain network in schizophrenia
These findings support the network dysregulation model of AVH in schizophrenia and demonstrate that rTMS can modulate AVH-related connectivity, partially restoring network efficiency. The inclusion of HCs provides evidence that rTMS-induced changes align with normative network patterns, and the responder analysis suggests that connectivity modulation is linked to clinical improvement. This study offers new insights into the neurobiological mechanisms of rTMS treatment and underscores the need for biomarker-driven, individualized neuromodulation strategies for schizophrenia.
Authors
- Weiliang Ye (ORCID: https://orcid.org/0000-0002-9904-5502)
- Ye Li (ORCID: https://orcid.org/0000-0002-6901-7105)
- Lin Zhang (ORCID: https://orcid.org/0009-0006-0896-8392)
- Jing Han (ORCID: https://orcid.org/0000-0003-1460-0114)
- Xiaohui Liu (ORCID: https://orcid.org/0000-0001-5211-0525)
- Yuanqiang Zhu (ORCID: https://orcid.org/0009-0000-3395-0115)
- Li Guo (ORCID: https://orcid.org/0000-0001-9541-8298)
- Chaozong Ma
Institutions
- Chinese People 's Liberation Army No. 85 Hospital (CN)
- Xijing Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-04-15
- DOI
- https://doi.org/10.3389/fpsyt.2025.1578072
- Citations
- 1
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.43