Immune checkpoint inhibitor outcomes and prognostic factors in gynecologic tract melanoma: a single-center analysis
This single-center study suggests that ICIs have limited efficacy in treating GTM, emphasizing the need for further investigation through larger, multicenter clinical trials. Prognostic factors such as FHC, AJCC stage, lymph node involvement, and LDH levels may aid in risk stratification and personalized treatment planning. However, due to the nature of this study, external cohorts are still needed for validation.
Authors
- Kemin Li (ORCID: https://orcid.org/0000-0001-8731-5846)
- Jing Zeng (ORCID: https://orcid.org/0000-0003-0857-2217)
- Rutie Yin (ORCID: https://orcid.org/0000-0002-9221-6727)
- Rui Li (ORCID: https://orcid.org/0000-0003-1044-1398)
- Jianzhang Wang (ORCID: https://orcid.org/0000-0002-1757-2422)
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-15
- DOI
- https://doi.org/10.3389/fimmu.2025.1542293
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Sichuan University
- Sichuan Province Science and Technology Support Program