Multi-trait GWAS identifies pleiotropic loci associated with colorectal cancer in East Asian populations

Our study identifies novel pleiotropic loci associated with CRC in East Asians, emphasizing the importance of population-specific genetic studies. The findings provide new insights into the genetic architecture of CRC and its shared pathways with other complex diseases.

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Publication Details

Journal
Frontiers in Genetics
Published
2025-04-15
DOI
https://doi.org/10.3389/fgene.2025.1590652
Citations
1
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
1.82
Controls
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article

Multi-trait GWAS identifies pleiotropic loci associated with colorectal cancer in East Asian populations

Peng Zhong, Yong Zhu, Xiqi Chen, Guangdong Xie
1 citations
Frontiers in Genetics
Genetic Associations and Epidemiology
1.82
article

Multi-trait GWAS identifies pleiotropic loci associated with colorectal cancer in East Asian populations

Peng Zhong, Yong Zhu, Xiqi Chen, Guangdong Xie
article en
1 citations

Abstract

Our study identifies novel pleiotropic loci associated with CRC in East Asians, emphasizing the importance of population-specific genetic studies. The findings provide new insights into the genetic architecture of CRC and its shared pathways with other complex diseases.

Frontiers in GeneticsVol. 16
Shandong University of Traditional Chinese Medicine (CN), Jining First People's Hospital (CN), Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 17%
Genetic Associations and Epidemiology
1.82
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Multi-trait GWAS identifies pleiotropic loci associated with colorectal cancer in East Asian populations — Peng Zhong, Yong Zhu, et al. · Frontiers in Genetics (2025) | TGRS Research Map | TGRS