Gold and Silver Nanoparticles Efficiently Modulate the Crosstalk Between Macrophages and Cancer Cells
Both AuNPs and AgNPs showed a remarkable ability to influence macrophage-cancer cell communication, suppressed indirectly M2-like TAM polarization, and perturbed the migration behavior of TAMs that is critical for tumor invasion, indicating modulated immunological functions and debilitated cancer-promoting capabilities of TAMs in this microenvironment.
Authors
- Nóra Igaz (ORCID: https://orcid.org/0000-0003-1580-4397)
- Csaba Vízler (ORCID: https://orcid.org/0009-0005-2750-8845)
- Andrea Rónavári (ORCID: https://orcid.org/0000-0001-7054-0975)
- Dóra Izabella Adamecz (ORCID: https://orcid.org/0000-0002-1883-9600)
- Attila Gácser (ORCID: https://orcid.org/0000-0003-2939-9580)
- Éva Veres (ORCID: https://orcid.org/0000-0002-1892-0329)
- Csaba Papp (ORCID: https://orcid.org/0000-0003-4450-0667)
- Annamária Marton (ORCID: https://orcid.org/0009-0005-0490-3359)
- Mónika Kiricsi (ORCID: https://orcid.org/0000-0002-8416-2052)
- Zoltán Kónya (ORCID: https://orcid.org/0000-0002-9406-8596)
- Hédi Árva
Institutions
- University of Szeged (HU)
- HUN-REN Szegedi Biológiai Kutatóközpont (HU)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/ijn.s508171
- Citations
- 4
- Primary Topic
- Nanoparticles: synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 2.07