Carbon‐ion irradiation together with autophagy inhibition and immune checkpoint inhibitors protect against pancreatic cancer development in mouse model
Treg cell-targeted therapy exerted an anticancer effect in mice bearing CIRT+HCQ-treated tumors but not in those bearing untreated pancreatic tumors by activating cancer-specific CD8<sup>+</sup> T cells.
Authors
- Hiroko Tsutsui (ORCID: https://orcid.org/0000-0001-7928-4875)
- Jiro Fujimoto (ORCID: https://orcid.org/0000-0002-2757-9011)
- Keiko Mitani (ORCID: https://orcid.org/0000-0002-4439-9055)
- Jingren Wang (ORCID: https://orcid.org/0000-0002-1859-8018)
- Koubun Yasuda (ORCID: https://orcid.org/0000-0002-3533-1702)
- Makoto Sudo
- Shuhei Hayashi (ORCID: https://orcid.org/0000-0001-7004-7339)
- Yaoyao Wang (ORCID: https://orcid.org/0000-0002-2250-0378)
- Masaki Ohmuraya (ORCID: https://orcid.org/0000-0001-9707-3932)
Institutions
- Hyogo University (JP)
Publication Details
- Journal
- Journal of Hepato-Biliary-Pancreatic Sciences
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1002/jhbp.12148
- Citations
- 1
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Japan Society for the Promotion of Science