Novel specific binding of copper ions to naturally modified base pairs involving 5-fluorouracil in duplex DNA
Only mercury(II) and silver(I) ions are known to specifically bind to natural and naturally modified base pairs in duplex DNA to form metal-mediated base pairs. We found novel, specific binding of copper ions to naturally modified base pairs involving 5-fluorouracil (FdU) in duplex DNA, forming C-Cu-FdU and FdU-Cu-C base pairs.
Authors
- Jiro Kondo (ORCID: https://orcid.org/0000-0002-5682-3685)
- Saki Adachi (ORCID: https://orcid.org/0000-0003-0833-4462)
- Kei Hirabayashi
- Hidetaka Torigoe (ORCID: https://orcid.org/0000-0003-4742-6132)
Institutions
- Tokyo University of Science (JP)
- Sophia University (JP)
Publication Details
- Journal
- Dalton Transactions
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5dt00619h
- Primary Topic
- DNA and Nucleic Acid Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Paul Scherrer Institut
- Japan Society for the Promotion of Science