Advances in CAR-T cell therapy in HCC
Because of the limited efficacy of conventional therapies, Hepatocellular carcinoma (HCC) is a global health concern. A new therapeutic strategy, chimeric antigen receptor T-cells (CAR-T), has demonstrated considerable potential in treating HCC. This paper reviews the structure and mechanism and clinical application of CAR-T cells to treat HCC, with a particular focus on experimental research targeting different antigens and the combination of CAR-T CAR-T and other therapies.
Authors
- Dingyi Liu (ORCID: https://orcid.org/0009-0002-1865-7660)
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Biomedical Data Science
- Published
- 2025-01-01
- DOI
- https://doi.org/10.47297/wspbdswsp2752-630525.20250501
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00