Application and Effect Evaluation of Differential Privacy in Genomic Data Medical Services

Genomic data is increasingly widely used in the medical service field, bringing new opportunities for medical development. However, the issue of privacy protection has become prominent, hindering further applications. Differential privacy technology provides a new idea to solve this problem, as it can maintain data availability while ensuring privacy. This article analyzes the threats of genomic data privacy leakage, covering sequencing storage, research analysis, and clinical medical service processes. It elaborates on the differential privacy method, including its formal definition, indistinguishability and other characteristics, and evaluates the application effect in combination with research cases such as pharmacogenomics and personalized medicine. Currently, in practical applications, there are still challenges such as balancing privacy and data utility, technology scalability, and privacy budget setting. In the future, this technology will develop in the direction of integration and innovation with other technologies, expanding application scenarios, and realizing standardization and normalization, and is expected to provide stronger privacy protection support for precision medicine.

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Publication Details

Journal
Biomedical Data Science
Published
2025-01-01
DOI
https://doi.org/10.47297/wspbdswsp2752-630509.20250501
Primary Topic
Medical Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Application and Effect Evaluation of Differential Privacy in Genomic Data Medical Services

Yu Yan
Biomedical Data Science
Medical Research and Treatments
article

Application and Effect Evaluation of Differential Privacy in Genomic Data Medical Services

Yu Yan
article en

Abstract

Genomic data is increasingly widely used in the medical service field, bringing new opportunities for medical development. However, the issue of privacy protection has become prominent, hindering further applications. Differential privacy technology provides a new idea to solve this problem, as it can maintain data availability while ensuring privacy. This article analyzes the threats of genomic data privacy leakage, covering sequencing storage, research analysis, and clinical medical service processes. It elaborates on the differential privacy method, including its formal definition, indistinguishability and other characteristics, and evaluates the application effect in combination with research cases such as pharmacogenomics and personalized medicine. Currently, in practical applications, there are still challenges such as balancing privacy and data utility, technology scalability, and privacy budget setting. In the future, this technology will develop in the direction of integration and innovation with other technologies, expanding application scenarios, and realizing standardization and normalization, and is expected to provide stronger privacy protection support for precision medicine.

Biomedical Data ScienceVol. 5(1)
Jiujiang University (CN)
Gender equality
Openalex Percentile: Top 88%
Medical Research and Treatments
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