Decoding immune cell dynamics in ischemic stroke: insights from single-cell RNA sequencing analysis
This study demonstrated that phagocytosis in IS cell types critically influences disease progression. It also predicted the trajectories of infarct cells. These findings provide valuable insights into the molecular and cellular mechanisms underlying IS and highlight potential pathways for therapeutic intervention.
Authors
- Yaobin Long (ORCID: https://orcid.org/0000-0001-9093-0399)
- Qi Huang (ORCID: https://orcid.org/0000-0002-0261-4562)
- Mika Pan (ORCID: https://orcid.org/0000-0002-8133-0241)
- Yating Lan (ORCID: https://orcid.org/0009-0007-3476-5801)
- Wenyi Song
- Donghua Zou (ORCID: https://orcid.org/0000-0002-3891-9472)
- Wei Qin (ORCID: https://orcid.org/0000-0003-2161-387X)
- Guining Liang
- Jingyi Zeng
- Chun Zou (ORCID: https://orcid.org/0000-0002-7734-515X)
- Feiyu Nong
Institutions
- Guangxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-04-15
- DOI
- https://doi.org/10.3389/fnagi.2025.1549518
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.84