Investigating Risk of Cancer with Sodium-Glucose Cotransporter 2 Inhibitors: A Disproportionality Analysis in the WHO Global Pharmacovigilance Database Vigibase®
In this disproportionality analysis with a hypothesis-generating approach, SGLT-2is are associated with an increased risk of reporting bladder and kidney cancer. There is a need of an urgent clarification of this signal with further long-term observational studies.
Authors
- Frédéric Bouisset (ORCID: https://orcid.org/0000-0001-8642-0273)
- François Montastruc (ORCID: https://orcid.org/0000-0001-7056-8126)
- Meyer Elbaz (ORCID: https://orcid.org/0000-0002-3520-7883)
- Fabien Despas (ORCID: https://orcid.org/0000-0002-3116-9963)
- Paul Gautier (ORCID: https://orcid.org/0009-0008-9934-8432)
Institutions
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Toulouse Mathematics Institute (FR)
- Pharmacochimie et Biologie pour le Développement (FR)
Publication Details
- Journal
- Drug Safety
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1007/s40264-025-01546-5
- Citations
- 5
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 6.47
Funders
- Université de Toulouse