Challenges in Diagnosing Necrotizing Sarcoid Granulomatosis: The First Case Reported From Indonesia
Necrotizing sarcoid granulomatosis (NSG) is a rare disease characterized by granulomatous and necrotic features as well as vasculitis, and it primarily affects the lungs, with occasional extrapulmonary manifestations. The first documented case was in Jakarta, Indonesia. A 71-year-old male presented with prolonged fever, a neck mass, and multiple mediastinal lymphadenopathy. The disease was initially suspected as lung tuberculosis, but a surgical biopsy of the left thyroid lobe confirmed the NSG pattern. Treatment with oral prednisolone led to positive outcomes, as evidenced by radiological improvement at the 3-month follow-up. This case report aims to emphasize the challenges and the importance of clinician awareness in diagnosing NSG.
Authors
- Rina La Distia Nora (ORCID: https://orcid.org/0000-0002-7026-5341)
- Gurmeet Singh (ORCID: https://orcid.org/0000-0002-0734-0660)
- Cleopas Martin Rumende (ORCID: https://orcid.org/0000-0002-7305-7337)
- Ralph Girson Gunarsa
- Fajar Lamhot Gultom
- Soedarman Sjamsoe
- Ceva Wicaksono Pitoyo (ORCID: https://orcid.org/0000-0002-2138-5814)
- Muhammad Rizki Triono (ORCID: https://orcid.org/0009-0009-2746-4546)
- Ramadhan Karsono
- Devi Felicia
- Daniel Ruslim
- Arif Sejati
Institutions
- Universitas Kristen Indonesia (ID)
- Tarumanagara University (ID)
- Atma Jaya Catholic University of Indonesia (ID)
- Pertamina (Indonesia) (ID)
- University of Indonesia (ID)
- National Brain Centre (ID)
- Dharmais Cancer Hospital (ID)
- Siloam Eye Hospital (KR)
- Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (ID)
Publication Details
- Journal
- Case Reports in Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/carm/3219868
- Citations
- 1
- Primary Topic
- Sarcoidosis and Beryllium Toxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 1.16