Case Report: Agranulocytosis in a Child Following Metamizole Use – A Diagnostic Challenge

In cases of agranulocytosis, involving a prolonged history of metamizole use accompanied by the presence of blast cells and granulocyte precursors in peripheral blood, we would recommend an initial diagnostic approach that includes a complete blood count with differential and flow cytometry of peripheral blood. Bone marrow aspiration may be postponed or deemed unnecessary if peripheral blood flow cytometry shows no aberrant populations and there are no other signs of leukaemia.

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Publication Details

Journal
Acta Medica Academica
Published
2025-04-15
DOI
https://doi.org/10.5644/ama2006-124.472
Citations
1
Primary Topic
Blood disorders and treatments
Type
article
Field-Weighted Citation Impact
1.82
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article

Case Report: Agranulocytosis in a Child Following Metamizole Use – A Diagnostic Challenge

Tomaž Prelog, Janez Jazbec, Alenka Trampuš Bakija, Aljaž Pirnat
1 citations
Acta Medica Academica
Blood disorders and treatments
1.82
article

Case Report: Agranulocytosis in a Child Following Metamizole Use – A Diagnostic Challenge

Tomaž Prelog, Janez Jazbec, Alenka Trampuš Bakija, Aljaž Pirnat
article en
1 citations

Abstract

In cases of agranulocytosis, involving a prolonged history of metamizole use accompanied by the presence of blast cells and granulocyte precursors in peripheral blood, we would recommend an initial diagnostic approach that includes a complete blood count with differential and flow cytometry of peripheral blood. Bone marrow aspiration may be postponed or deemed unnecessary if peripheral blood flow cytometry shows no aberrant populations and there are no other signs of leukaemia.

Acta Medica AcademicaVol. 54(1)
Ljubljana University Medical Centre (SI)
Good health and well-being
Openalex Percentile: Top 17%
Blood disorders and treatments
1.82
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