Association between vitamin D receptor gene polymorphisms, inflammatory cytokines (IL-1, IL-6, and IL-10), and fracture healing in sports-related injuries

A retrospective analysis was conducted on 110 patients with SRF admitted to our hospital from February 2023 to October 2023. Among these, 41 patients with poor fracture healing (research group) and 69 patients with good fracture healing (control group) were included. Serum levels of Vitamin D (VD), bone mineral density (BMD), and inflammatory cytokines (IL-1, IL-6, and IL-10) were measured to assess their relationship with fracture healing. Additionally, polymorphisms in the VDR gene at the Apa I and FoK I loci were analysed to determine the differences between the two groups.