A Complex Infectious Case of Dengue Fever with Thrombocytopenia, Acute Hepatitis A, Influenza B, URTI(Upper Respiratory Tract Infection), and Secondary HLH (Hemophagocytic Lymphohistiocytosis): A Diagnostic Challenge

Worldwide, dengue is the most frequent trigger for viral haemorrhagicfever. Although it is chronic in many tropical nations, instances fromnon-endemic areas have also been documented on a regular basis inrecent years. Nonetheless, the World Health Organization’s revisedclassification of dengue splits it into three groups: severe dengue,dengue with warning signals, and dengue without warning signs.Significant dengue is defined as those who have a significant vascularleak, hypotension, severe bleeding, or severe organ involvement.Hepatitis, the influenza virus, respiratory infections, liver failure, andHemophagocytic lymphohistiocytosis (HLH) linked to dengue feverhave all been documented; most of these cases involved children, witha small number of adult case reports. Fatal results including a 50%mortality rate have been documented in the child’s research. Here wehave presented a case of a 17-year-old teenager with dengue fever andco-morbidities of hepatitis, influenza, lung diseases, and HLH. How to cite this article:Gadhiya H, Radhanpura Y, Parekh K, Trigar P.A Complex Infectious Case of Dengue Feverwith Thrombocytopenia, Acute Hepatitis A,Influenza B, URTI(Upper Respiratory TractInfection), and Secondary HLH (HemophagocyticLymphohistiocytosis): A Diagnostic Challenge. JCommun Dis. 2025;57(1):213-216. DOI: https://doi.org/10.24321/0019.5138.202527