Exploration of the Mechanism and New Therapeutic Approaches of Insomnia Caused by Disharmony of the Spleen and Stomach

以中医理论阐述脾胃生理功能、失眠认识及二者相关经典论述；探究脾胃不和致失眠机制，如气血不足、升降失常、痰湿内生与情志关联；总结临床研究现状，涵盖观察和治疗研究；指出当前研究样本量小、方法单一等不足，展望未来多中心大样本及多学科交叉研究方向，旨在为后续科研和临床治疗提供参考。This paper reviews the relationship between disharmony of the spleen and stomach and insomnia. It expounds on the physiological functions of the spleen and stomach, the understanding of insomnia in traditional Chinese medicine theory, and the classic discussions related to the two. The mechanisms by which disharmony of the spleen and stomach leads to insomnia are analyzed, including insufficient qi and blood, abnormal ascending and descending, internal generation of phlegm-dampness, and the connection with emotions. The current status of clinical research is summarized, covering both observational and treatment studies. It points out the deficiencies of current research, such as small sample sizes and single research methods, and looks ahead to the future research directions of multi-center large-sample and multidisciplinary cross-research, aiming to provide reference for subsequent scientific research and clinical treatment.