SF3B4 regulates proliferation and apoptosis in hepatocellular carcinoma via alternative splicing and interaction with TRIM28 and SETD5
SF3B4 contributes to HCC progression by directly binding mRNAs and interacting with proteins, thereby regulating gene expression and alternative splicing.
Authors
- Yuqi Wen (ORCID: https://orcid.org/0000-0002-2391-3297)
- Hanfei Huang (ORCID: https://orcid.org/0000-0003-3302-823X)
- Haijing Li (ORCID: https://orcid.org/0000-0001-9332-8993)
- S. Qu
- Kai Gan (ORCID: https://orcid.org/0000-0001-8414-7242)
- Chaochi Yue
- ZhiTao Li
- Yuan Fang
- Bo Yuan (ORCID: https://orcid.org/0000-0003-4544-7802)
- Zhong Zeng
Institutions
- Kunming Medical University (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1186/s12967-025-06420-7
- Citations
- 3
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- National Natural Science Foundation of China
- Kunming Medical University
- Natural Science Foundation of Yunnan Province
- Yunnan Provincial Department of Education
- Yunnan Provincial Department of Education Science Research Fund Project