Inclusive Drug Designing of Novel Indole Derivatives using Rationale, Pharmacophore Mapping and Molecular Docking
The novel-designed lead molecules demonstrate an enhanced pharmacokinetic profile, superior binding affinity, and minimal toxicity, based on computational study. These attributes make them promising candidates for further optimization as glucokinase activators.
Authors
- Rekha Sangwan (ORCID: https://orcid.org/0000-0002-0106-4319)
- Rahul K. Sharma (ORCID: https://orcid.org/0000-0003-3120-6194)
- Amit Mittal (ORCID: https://orcid.org/0000-0001-9689-1642)
- Anuradha Mehra
- Aryan Mehra
Institutions
- Lovely Professional University (IN)
Publication Details
- Journal
- Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
- Published
- 2025-04-15
- DOI
- https://doi.org/10.2174/0118715230352441250309014403
- Citations
- 2
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 4.01