Decoding the Molecular Mechanisms of miRNAs: Protein Interactions in Schizophrenia Pathogenesis

Schizophrenia is now diagnosed mostly based on symptoms and physical signs rather than the patient's pathological and physiological markers. While oncologists once felt satisfied when their patients experienced a long remission, today, they are leading research into innovative treatments with molecularly targeted drugs, as well as strategies to enhance diagnostic accuracy and alleviate symptoms as the disease advances. Because biomarkers reflect an organism's physiological, physical, and biochemical state, they are very beneficial and have a wide range of real-- world uses. The identification of blood biomarkers may open up new avenues for studying schizophrenia. MicroRNAs (miRNAs) may serve as diagnostic indicators for schizophrenia as their abnormal expression has recently been linked to the disease's pathophysiology. The precise etiological process of schizophrenia remains largely unknown despite the general agreement that developmental and genetic factors play a critical role in the pathophysiology of the disorder. miRNAs have gained recognition as an essential post-transcriptional regulator in the regulation of gene expression in recent decades. The importance of miRNAs for brain development and neuroplasticity is well established.

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Publication Details

Journal
Current Protein and Peptide Science
Published
2025-04-15
DOI
https://doi.org/10.2174/0113892037362309250319035758
Citations
3
Primary Topic
MicroRNA in disease regulation
Type
article
Field-Weighted Citation Impact
2.81
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article

Decoding the Molecular Mechanisms of miRNAs: Protein Interactions in Schizophrenia Pathogenesis

Lavanya Lakshminarayana, Samy Selim, Sanjesh Kumar, Rashmi Pathak et al.
3 citations
Current Protein and Peptide Science
MicroRNA in disease regulation
2.81
article

Decoding the Molecular Mechanisms of miRNAs: Protein Interactions in Schizophrenia Pathogenesis

Lavanya Lakshminarayana, Samy Selim, Sanjesh Kumar, Rashmi Pathak, Soad K. Al Jaouni, Subhajit Mandal, Anas Islam, B. Sharma, Radheshyam Pal, Sumel Ashique, Mansi Singh, Amisha S. Raikar, Himanshu Sharma
article en
3 citations

Abstract

Schizophrenia is now diagnosed mostly based on symptoms and physical signs rather than the patient's pathological and physiological markers. While oncologists once felt satisfied when their patients experienced a long remission, today, they are leading research into innovative treatments with molecularly targeted drugs, as well as strategies to enhance diagnostic accuracy and alleviate symptoms as the disease advances. Because biomarkers reflect an organism's physiological, physical, and biochemical state, they are very beneficial and have a wide range of real-- world uses. The identification of blood biomarkers may open up new avenues for studying schizophrenia. MicroRNAs (miRNAs) may serve as diagnostic indicators for schizophrenia as their abnormal expression has recently been linked to the disease's pathophysiology. The precise etiological process of schizophrenia remains largely unknown despite the general agreement that developmental and genetic factors play a critical role in the pathophysiology of the disorder. miRNAs have gained recognition as an essential post-transcriptional regulator in the regulation of gene expression in recent decades. The importance of miRNAs for brain development and neuroplasticity is well established.

Current Protein and Peptide ScienceVol. 26(8)
JSS Academy of Higher Education and Research (IN), Teerthanker Mahaveer University (IN), King Abdulaziz University (SA), Integral University (IN), Invertis University (IN), Jouf University (SA), Dibrugarh University (IN), GLA University (IN), REVA University (IN)
Good health and well-being
Openalex Percentile: Top 10%
MicroRNA in disease regulation
2.81
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