Transcriptomic and metabolomic insights into neutrophil activity in COPD complicated by metabolic syndrome
COPD patients with metabolic syndrome exhibit a heightened neutrophil-mediated inflammatory response and significant metabolic disturbances, which underscores the need for precise therapeutic strategies targeting both metabolic and inflammatory pathways to improve patient outcomes and manage COPD-MS complexities effectively.
Authors
- Xue Wu (ORCID: https://orcid.org/0000-0002-5567-1325)
- Xiang He (ORCID: https://orcid.org/0000-0002-7690-0289)
- Yi Zhang (ORCID: https://orcid.org/0000-0002-4057-678X)
- Yuting Fu (ORCID: https://orcid.org/0000-0002-8667-8298)
- Jie Gao (ORCID: https://orcid.org/0000-0002-5189-8338)
- Guoping Li (ORCID: https://orcid.org/0000-0003-3360-6124)
- Juan Li (ORCID: https://orcid.org/0000-0002-7489-4778)
- Yao Liu (ORCID: https://orcid.org/0000-0001-6750-9950)
- Junyi Wang (ORCID: https://orcid.org/0000-0003-0464-4543)
- Jiahuan Li (ORCID: https://orcid.org/0000-0002-0016-7682)
- Jiliu Liu
- Bomiao Qing
Institutions
- North Sichuan Medical University (CN)
- Macau University of Science and Technology (MO)
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- BioMedical Engineering OnLine
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1186/s12938-025-01378-5
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Chengdu Science and Technology Bureau
- Natural Science Foundation of Sichuan Province