Association of ABC Efflux Transporter Genetic Variants and Adverse Drug Reactions and Survival in Patients with Non-Small Lung Cancer
The data suggest that <i>ABCB1</i> variants may influence gastrointestinal ADRs and patient survival, highlighting the importance of pharmacogenomics in predicting ADRs and drug resistance. This approach offers more precise pharmacotherapy, reduces ADRs, and enhances the patients' quality of life and survival.
Authors
- Maurício Wesley Perroud (ORCID: https://orcid.org/0000-0001-5984-9947)
- Cecília Souto Seguin (ORCID: https://orcid.org/0000-0003-1999-4968)
- Eder de Carvalho Pincinato (ORCID: https://orcid.org/0000-0002-1602-7318)
- Patrícia Moriel (ORCID: https://orcid.org/0000-0002-4927-7022)
- Carolina Dagli-Hernandez (ORCID: https://orcid.org/0000-0003-2109-9399)
- Pedro Eduardo Nascimento Silva Vasconcelos (ORCID: https://orcid.org/0000-0001-8428-4124)
- Mariana Vieira Morau (ORCID: https://orcid.org/0000-0002-7423-1413)
- Giovana Fernanda Santos Fidelis (ORCID: https://orcid.org/0000-0002-9867-389X)
- Yasmim Gabriele Matos (ORCID: https://orcid.org/0000-0002-6729-5216)
Institutions
- Universidade de São Paulo (BR)
- Universidade Estadual de Campinas (UNICAMP) (BR)
Publication Details
- Journal
- Genes
- Published
- 2025-04-15
- DOI
- https://doi.org/10.3390/genes16040453
- Citations
- 1
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Universidade Estadual de Campinas