Deciphering Gut Microbiome in Colorectal Cancer via Robust Learning Methods
Biologically, the microbial signatures identified from the integrated data improve our understanding of the gut microbiota's role in CRC pathogenesis and may contribute to the development of translational targets and microbiota-based therapies. Methodologically, this study demonstrates the effectiveness of adapting robust techniques from single-cell research to improve the precision of microbial marker discovery.
Authors
- Hongwei Han (ORCID: https://orcid.org/0000-0002-8410-4389)
- Wodan Ling (ORCID: https://orcid.org/0000-0001-7196-8543)
- Youran Qi
- Stefano Mangiola (ORCID: https://orcid.org/0000-0001-7474-836X)
- Ying Li (ORCID: https://orcid.org/0000-0001-5429-0080)
Institutions
- Walter and Eliza Hall Institute of Medical Research (AU)
- Cornell University (US)
- Centre for Cancer Biology (AU)
- Weill Cornell Medicine (US)
- The University of Adelaide (AU)
Publication Details
- Journal
- Genes
- Published
- 2025-04-15
- DOI
- https://doi.org/10.3390/genes16040452
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Institute of General Medical Sciences