Effective Treatment of Janus Kinase 1/3 Inhibitor in Blau Syndrome From a Multicenter Retrospective Study in Central China

TOF could be an effective therapeutic option for patients with BS who demonstrate resistance to TNFi or corticosteroids. Specifically, the <i>STAT3</i> rs2293152 GG polymorphism was associated with improved response to treatment, suggesting a genotype-influenced therapeutic efficacy.

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Publication Details

Journal
The Journal of Rheumatology
Published
2025-04-15
DOI
https://doi.org/10.3899/jrheum.2024-0822
Primary Topic
Sarcoidosis and Beryllium Toxicity Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Effective Treatment of Janus Kinase 1/3 Inhibitor in Blau Syndrome From a Multicenter Retrospective Study in Central China

Wen Yin, Yangyang Hu, Pengcheng Li, Xiong Zhang et al.
The Journal of Rheumatology
Sarcoidosis and Beryllium Toxicity Research
article

Effective Treatment of Janus Kinase 1/3 Inhibitor in Blau Syndrome From a Multicenter Retrospective Study in Central China

Wen Yin, Yangyang Hu, Pengcheng Li, Xiong Zhang, Jinhua Liu, Hai Xu, Jing Cai, Yikai Yu, Zhipeng Zeng
article en

Abstract

TOF could be an effective therapeutic option for patients with BS who demonstrate resistance to TNFi or corticosteroids. Specifically, the <i>STAT3</i> rs2293152 GG polymorphism was associated with improved response to treatment, suggesting a genotype-influenced therapeutic efficacy.

The Journal of RheumatologyVol. 52(8)
Yunnan University (CN), Wuhan No.1 Hospital (CN), Wuhan Union Hospital (CN), Wuhan Children's Hospital (CN), Tongji Hospital (CN), Union Hospital (CN), Huazhong University of Science and Technology (CN), Hubei University (CN)
Good health and well-being
Openalex Percentile: Top 90%
Sarcoidosis and Beryllium Toxicity Research
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