The Pomegranate Flower Water Extract Negatively Regulates Melanogenesis by Suppressing MITF Expression and Its Target Enzymes
Pomegranate flower extract possessed a strong antimelanogenesis effect, which resulted from inhibiting the expression of MITF and its downstream target enzymes involved in melanin synthesis. These findings provide a strong scientific basis for the use of PFE as a safe and effective skin-lightening ingredient in the cosmetic industry.
Authors
- Nuermaimaiti Abudukelimu
- Peng Shu (ORCID: https://orcid.org/0009-0004-6354-8716)
- Deng Zang
- Yuan Wang (ORCID: https://orcid.org/0000-0002-5692-2659)
- Nannan Xu (ORCID: https://orcid.org/0000-0003-2847-7225)
- Jiangyu Zhao
- Parida Aiziti
Institutions
- Chinese Academy of Sciences (CN)
- Xinjiang Technical Institute of Physics & Chemistry (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Journal of Cosmetic Dermatology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1111/jocd.70163
- Citations
- 1
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 1.15