Clinical outcomes of pregnancy in patients with pulmonary hypertension: A single center observational study

Severe PH and high NT-proBNP levels are strongly correlated with increased maternal mortality rates in pregnant women. Conception should be contraindicated in cases of severe PAH with elevated NT-proBNP levels. In situations where unplanned pregnancy occurs in severe PAH patients with decompensated heart function, early pregnancy termination and multidisciplinary management are crucial to ensure maternal safety. However, pregnancy should be considered individually in women with moderate and mild PH and preserved right heart function.