Evaluating Risk Factors for Early-Onset Colorectal Cancer in a Large, Prospective Cohort
Within this study, we find that genetic risk variants are a significant driver of EOCRC risk. Accelerated aging appears to be associated with increased risk of both EOCRC and LOCRC, and measures such as PhenoAge warrant continued study.
Authors
- Sunny Sandhu (ORCID: https://orcid.org/0000-0002-2530-5885)
- Catherine Blandon (ORCID: https://orcid.org/0000-0001-6414-6787)
- Shria Kumar (ORCID: https://orcid.org/0000-0001-9745-2676)
Institutions
- University of Miami (US)
Publication Details
- Journal
- Digestive Diseases and Sciences
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1007/s10620-025-09055-2
- Citations
- 3
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 3.14
Funders
- Conquer Cancer Foundation
- American Society of Clinical Oncology
- University of Miami
- Sylvester Comprehensive Cancer Center, University of Miami Health Systems