Macrophage Depletion Reduces Bone Loss and Alters Inflammatory Responses: A Mouse Peri‐Implantitis Model
Macrophage depletion effectively reduces bone loss and inflammation in peri-implantitis. This study highlights targeting macrophages as a promising approach for managing peri-implantitis, although further research is needed to optimize therapeutic strategies.
Authors
- Ofir Ginesin (ORCID: https://orcid.org/0000-0002-8736-9753)
- Ofri Doppelt‐Flikshtain
- Benjamin R. Coyac (ORCID: https://orcid.org/0000-0003-0105-6703)
- Eran Gabay (ORCID: https://orcid.org/0000-0003-0429-2883)
- Yotam Bar‐On (ORCID: https://orcid.org/0000-0003-4378-707X)
- Hadar Zigdon‐Giladi (ORCID: https://orcid.org/0000-0002-4940-6533)
- Tal Berg
- Yaniv Mayer (ORCID: https://orcid.org/0000-0001-5500-7961)
Institutions
- Tel Aviv University (IL)
- Technion – Israel Institute of Technology (IL)
- Rambam Health Care Campus (IL)
Publication Details
- Journal
- Journal Of Clinical Periodontology
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1111/jcpe.14120
- Citations
- 3
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 2.02
Funders
- International Team for Implantology
- ITI Foundation