Maternal Immunization Against SARS-CoV-2 and Infant Immunity Persistence in a Brazilian Cohort

From January 2021 to March 2022, we studied antibody transfer and persistence in infants of SARS-CoV-2-infected or vaccinated pregnant women in Brazil. Third-trimester vaccination increased maternal anti-S immunoglobulin G, correlating with cord and infant levels at 6 months. Neutralizing antibody were detected only in vaccinated mothers and cord blood, persisting in only 2 infants at 6 months.

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Publication Details

Journal
The Pediatric Infectious Disease Journal
Published
2025-04-09
DOI
https://doi.org/10.1097/inf.0000000000004817
Primary Topic
COVID-19 Impact on Reproduction
Type
article
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article

Maternal Immunization Against SARS-CoV-2 and Infant Immunity Persistence in a Brazilian Cohort

Maria Francilene Souza Silva, Fábio Miyajima, Remo Castro Russo, Germana Silva Vasconcelos et al.
The Pediatric Infectious Disease Journal
COVID-19 Impact on Reproduction
article

Maternal Immunization Against SARS-CoV-2 and Infant Immunity Persistence in a Brazilian Cohort

Maria Francilene Souza Silva, Fábio Miyajima, Remo Castro Russo, Germana Silva Vasconcelos, Letícia Régia Lima Cavalcante, Renata Castro Kehdi, Deniele Bezerra Lós, Marcela Helena Gambim Fonseca, Veridiana Pessoa, Natália Gindri Fiorenza, Danielle S. Macêdo, Francisco Herlânio Costa Carvalho, Marylane da Silva Viana, Isabel Leite
article en

Abstract

From January 2021 to March 2022, we studied antibody transfer and persistence in infants of SARS-CoV-2-infected or vaccinated pregnant women in Brazil. Third-trimester vaccination increased maternal anti-S immunoglobulin G, correlating with cord and infant levels at 6 months. Neutralizing antibody were detected only in vaccinated mothers and cord blood, persisting in only 2 infants at 6 months.

The Pediatric Infectious Disease JournalVol. 44(7)
Universidade Federal de Minas Gerais (BR), Universidade Federal do Ceará (BR), Hospital Geral de Fortaleza (BR), Fundação Oswaldo Cruz (BR)
Good health and well-being
Openalex Percentile: Top 90%
COVID-19 Impact on Reproduction
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Maternal Immunization Against SARS-CoV-2 and Infant Immunity Persistence in a Brazilian Cohort — Maria Francilene Souza Silva, Fábio Miyajima, et al. · The Pediatric Infectious Disease Journal (2025) | TGRS Research Map | TGRS