Rationale and Design of an Exploratory, Randomized, Open-Label, Multicenter Clinical Trial to Investigate the Efficacy of Long-Acting β2-Agonist/Long-Acting Muscarinic Antagonist on Heart Failure Complicated by Chronic Obstructive Pulmonary Disease (
The COPD-HF trial will investigate the efficacy of LAMA/LABA on HF in patients with COPD and CHF.
Authors
- Hiroya Hayashi (ORCID: https://orcid.org/0000-0003-3053-0670)
- Shigeru Toyoda (ORCID: https://orcid.org/0000-0002-8260-833X)
- Hiroki Fukuda (ORCID: https://orcid.org/0000-0003-1483-5984)
- Takafumi Nakayama (ORCID: https://orcid.org/0000-0003-3529-6238)
- Yohei Hanajima (ORCID: https://orcid.org/0000-0003-4214-2886)
- Makoto Sata
- Takashi Sozu (ORCID: https://orcid.org/0000-0002-9857-5819)
- Masafumi Watanabe (ORCID: https://orcid.org/0000-0003-1278-9021)
- Shin Ito (ORCID: https://orcid.org/0000-0001-9731-8282)
- Mutsuo Horii (ORCID: https://orcid.org/0009-0003-8265-8710)
- Moriaki Inoko (ORCID: https://orcid.org/0000-0003-1388-4899)
- Noriyuki Ikehara
- Masafumi Kitakaze (ORCID: https://orcid.org/0000-0001-5157-4213)
- Yukio Abe (ORCID: https://orcid.org/0000-0002-6775-6940)
- Daiju Fukuda
- Chisato Izumi (ORCID: https://orcid.org/0000-0002-3282-1327)
- Yasuhiro Izumiya (ORCID: https://orcid.org/0000-0003-2332-9151)
- Masashi Yokoi
- Kohei Fujimoto
Institutions
- Yamagata University (JP)
- Tokyo University of Science (JP)
- Yokohama City University Medical Center (JP)
- Nagoya City University (JP)
- Osaka City General Hospital (JP)
- Ishikiriseiki Hospital (JP)
- National Cerebral and Cardiovascular Center (JP)
- Hanwa Memorial Hospital (JP)
- Kitano Hospital (JP)
- Medical Research Foundation (GB)
- Dokkyo Medical University (JP)
- Yokohama City University (JP)
- Kumamoto University (JP)
Publication Details
- Journal
- Circulation Reports
- Published
- 2025-04-11
- DOI
- https://doi.org/10.1253/circrep.cr-25-0010
- Citations
- 1
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Cerebral and Cardiovascular Center