Multisystem Inflammatory Syndrome with Pericarditis After COVID-19: A Case Report and Review of the Literature

A 24-year-old Vietnamese male patient presented with fever, cough, sore throat, and body pain. Nineteen days previously, the patient experienced nasal discharge and SARS-CoV-2 PCR at local pharmacy was positive. Based on the post COVID-19 status and symptoms, the current diagnosis was multisystem inflammatory syndrome in adults (MIS-A). Treatment with cefazolin was initiated owing to the possibility of bacterial pharyngitis; however, the symptoms did not improve. Additionally, the patient developed pericarditis. Instead of symptomatic therapy, the symptons, in fact, worsened and the patient developed pericarditis. He was then initiated on treatment with a corticosteroid (methylprednisolone 2mg/kg/day by intravenous infusion) and oral aspirin (100mg/day). With this treatment, the patient recovered and was discharged on an oral corticosteroid (prednisolone 30mg/day). We discuss this case along with a review of the literature to underscore the importance of early recognition of MIS-A and the current status of its treatment.