A conserved terpene cyclase gene in Sanghuangporus for abscisic acid-related sesquiterpenoid biosynthesis
A sesquiterpene synthase gene, its associated BGC, and the biosynthetic pathway for a group of detected abscisic acid-related sesquiterpenoids in Sanghuangporus were predicted through genomic and metabolic data analyses. This study addresses a critical gap in understanding the genetic basis of sesquiterpenoid production in Sanghuangporus and offers insights for future research on engineering metabolic pathways to enhance sesquiterpenoid production for medicinal use.
Authors
- Yeongwoon Jin
- Abel Severin Lupala (ORCID: https://orcid.org/0000-0001-6354-8477)
- Chang Wan Seo (ORCID: https://orcid.org/0000-0002-5948-1836)
- Yoonhee Cho (ORCID: https://orcid.org/0000-0002-0743-0914)
- Sang Hee Shim (ORCID: https://orcid.org/0000-0002-0134-0598)
- Young Woon Lim (ORCID: https://orcid.org/0000-0003-2864-3449)
- Hyun Jin Cho (ORCID: https://orcid.org/0000-0002-4562-0436)
Institutions
- Seoul National University (KR)
- Marine Biodiversity Institute of Korea (KR)
- Sokoine University of Agriculture (TZ)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1186/s12864-025-11542-9
- Citations
- 3
- Primary Topic
- Fungal Biology and Applications
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- National Research Foundation
- Ministry of Education
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea