Immunological analysis of LC16m8 vaccine: preclinical and early clinical insights into mpox
This research was supported by AMED under Grant Numbers JP243fa727002, JP243fa727001s0703, and JP243fa627001h0003 (K.J.I), JP24jf0126002, JP24fk0108690, JP243fa627001h0003, and JP243fa727002 (K.S), JP243fa727002 (Y.T.), JP243fa727002 and JP243fa627007h0003 (Y.Y.), and by the Research Support Project for Life Science and Drug Discovery (BINDS) from AMED under Grant Number JP23ama121011 (J.T.), and JP23ama121010 (T.S.), and by the Ministry of Education, Culture, Sports, Science and Technology in Japan under Grant Number 23K06577 (E.S.). AMED under Grant Number JP233fa827017 and JP243fa827017 (F.Y.), JP22fk0108501 (M.K.).
Authors
- Kei Sato (ORCID: https://orcid.org/0000-0003-4367-6361)
- Taishi Onodera (ORCID: https://orcid.org/0000-0002-7079-3339)
- Yoshimasa Takahashi (ORCID: https://orcid.org/0000-0001-6342-4087)
- Burcu Temizoz (ORCID: https://orcid.org/0000-0002-5189-3529)
- Junichi Takagi (ORCID: https://orcid.org/0000-0002-1219-475X)
- Tatsuya Sawasaki (ORCID: https://orcid.org/0000-0002-7952-0556)
- Michinori Kohara (ORCID: https://orcid.org/0000-0002-2130-5837)
- Fumihiko Yasui
- Tomotaka Okamura
- Daichi Utsumi (ORCID: https://orcid.org/0000-0001-6602-8426)
- Eita Sasaki (ORCID: https://orcid.org/0000-0002-3384-7414)
- Ken J. Ishii (ORCID: https://orcid.org/0000-0002-6728-3872)
- Noriko Toyama‐Sorimachi (ORCID: https://orcid.org/0000-0003-3474-0456)
- Kaiwen Liu
- Hideo Negishi
- Yasuhiro Yasutomi (ORCID: https://orcid.org/0000-0001-8252-1448)
- Tomoya Hayashi (ORCID: https://orcid.org/0000-0003-3189-6463)
- Kouji Kobiyama (ORCID: https://orcid.org/0000-0002-5846-4807)
- Yu Kaku
- Ahmad Faisal Amiry
- Asuka Joy Tobuse
- Areej Sakkour
Institutions
- Tokyo Medical University (JP)
- National Institute of Infectious Diseases (JP)
- National Institute of Biomedical Innovation, Health and Nutrition (JP)
- Tokyo Metropolitan Institute of Medical Science (JP)
- Saitama International Medical Center (JP)
- Protein Research Foundation (JP)
- Ehime University (JP)
- The University of Tokyo (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- EBioMedicine
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1016/j.ebiom.2025.105703
- Citations
- 7
- Primary Topic
- Poxvirus research and outbreaks
- Type
- article
- Field-Weighted Citation Impact
- 7.25
Funders
- Japan Agency for Medical Research and Development
- Ministry of Education, Culture, Sports, Science and Technology