Sequential Infusion of Mesenchymal Stem Cell for Graft-Versus-Host Disease Prevention in Haploidentical Hematopoietic Stem Cell Transplantation: An Open-Label, Multicenter, Randomized Controlled Clinical Trial
Our findings suggest that sequential infusion of MSCs within 3 months after haplo-HSCT significantly reduced both the incidence and severity of cGVHD and aGVHD, manifesting as a better GRFS rate for patients.
Authors
- Ruihao Huang (ORCID: https://orcid.org/0000-0001-5806-4961)
- Ren Lin (ORCID: https://orcid.org/0000-0002-9402-0883)
- Qifa Liu (ORCID: https://orcid.org/0000-0003-4015-3952)
- Xiao‐Jun Huang (ORCID: https://orcid.org/0000-0002-2145-6643)
- Haixia Fu (ORCID: https://orcid.org/0000-0002-4485-5276)
- Li Gao (ORCID: https://orcid.org/0000-0002-5816-5970)
- Yimei Feng (ORCID: https://orcid.org/0000-0003-1904-791X)
- Lu Zhao (ORCID: https://orcid.org/0000-0002-5568-2884)
- Lidan Zhu (ORCID: https://orcid.org/0000-0002-1258-3544)
- Xiaoqi Wang (ORCID: https://orcid.org/0000-0001-8251-9102)
- Lu Wang (ORCID: https://orcid.org/0000-0002-8346-194X)
- Jia Liu (ORCID: https://orcid.org/0000-0001-9474-4139)
- Xi Zhang (ORCID: https://orcid.org/0000-0002-8548-2832)
- Ting Chen (ORCID: https://orcid.org/0000-0002-3228-9166)
- Yanqi Zhang (ORCID: https://orcid.org/0000-0002-0664-2114)
- Yuqing Liu (ORCID: https://orcid.org/0000-0002-6324-1296)
- Wen Qin (ORCID: https://orcid.org/0000-0001-8966-7722)
- Han Yao (ORCID: https://orcid.org/0000-0002-0156-6052)
- Lei Gao (ORCID: https://orcid.org/0000-0003-2336-976X)
- Xiaohui Zhang (ORCID: https://orcid.org/0000-0003-4730-256X)
- Peiyan Kong
- Cheng Zhang (ORCID: https://orcid.org/0000-0001-5386-4708)
- Yu Wang (ORCID: https://orcid.org/0000-0002-8159-8723)
Institutions
- Army Medical University (CN)
- Peking University (CN)
- Nanfang Hospital (CN)
- Xinqiao Hospital (CN)
- Peking University People's Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal of Clinical Oncology
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1200/jco-24-02119
- Citations
- 10
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 16.25